What is MCAD?

MCAD also known as Mast Cell Activation Syndrome is an immunological condition in which mast cells release chemical mediators which result in chronic allergic reactions including anaphylaxis. People that suffer from MCAD actually have a normal number of mast cells which makes this condition different than mastocytosis, however the symptoms can be similar. The problem is that the mast cells are hyperresponsive which can cause all sorts of symptoms including skin issues like flushing, cardiovascular issues like syncope, gastrointestinal issues like diarrhea, and respiratory issues like congestion.



Mast cell activation disorder (MCAD) is a disorder which is thought to be caused by a genetic mutation that results in these hyperreactive mast cells. It’s important to understand that you have control of your genetics through something called Epigenetics. If you’re not familiar with epigenetics, please check out Bruce Lipton’s research and books on it. Epigenetics focuses on the protein that surrounds our DNA which controls gene expression your body. Various toxins in our food and environment can negatively effect these proteins causing an expression of a gene. So you even worst case scenario you have the gene for MCAD, you’re body can suppress or express this gene based on your exposure to toxins. The key is to limit your exposure to toxins and increase your exposure to nutrients to positively effect your DNA.
Here’s my video on Gene Expression if you’d like to learn more:

Next, let’s look at the systems that control your Mast cells because you’re body can’t just haphazardly produce random amounts of these cells. Mast cells normally help protect you from disease and aid in wound healing by releasing substances such as histamine and leukotrienes. So this means that they’re part of your immune system which involves every system of your body. The problem with our immune systems is that they are extremely complex due to the involvement of bacteria, viruses and fungi. Doctors who just test the blood to examine the immune system are missing out on the bigger picture because they’re not looking at the body’s microflora which represents around 80% of our immune system. Bacteria outnumber your cells 10 to 1 and viruses outnumber bacteria 10 to 1.

If the microflora plays such a crucial role in our immune responses, we must look at things that can disrupt our microflora.
Medications that Disrupt your Microflora
•Birth Control Pills

Other Exposures to Antibiotics
Antibiotics are especially harmful because they kill both beneficial and pathological bacteria which upsets the delicate balance in your body. This allows fungi to take which use their hyphae (tendrils) to poke holes through the lining of the intestinal wall which leads to Leaky Gut. Even if you’re not taking prescription antibiotics you might be exposing your body to them in other ways if you’re eating meat that came from a Concentrated Animal Feeding Operation (CAFO). The feeding operations account for around 70 percent of the total antibiotic use in the US.

Glyphosate is another concern because it directly affects the bacteria in your intestinal tract.

“Glyphosate is a very powerful selective antibiotic that kills beneficial, but not pathogenic, microorganisms in the soil and intestine.”
“Residue levels permitted in food are 40 to 800 times the antibiotic threshold and concentrations shown in clinical studies to damage mammalian tissues.”

Dr. Stephanie Seneff,
Research scientist at the
Massachusetts Institute of Technology (MIT)

There are so many other things that can negatively affect our immune systems such as vaccinations which have been linked to all sorts of autoimmune diseases and cancers. Please watch the videos below if you’d like to learn more:


Why is the microflora so important and how could it possibly cause MCAD? I thought you might ask that. Here are just some of the functions of your microflora:
Functions of your Gut Flora
Digestion and absorption of carbohydrates
Production of vitamins
Absorption of minerals
Elimination of toxins
Distinguish between pathogens and non-harmful antigens
Keep harmful bacteria under control
Aid in production of antibodies to pathogens
Provide support to the Immune System

A good start to restoring your health would be to optimize your gut flora through a healthy organic, plant based diet. Here’s a video to get you started:

Obviously probiotics will be essential to restoring your microflora, but what would be even better than a probiotic supplement would be to consume properly fermented foods. One spoonful of fermented foods like sauerkraut contain more probiotics than an entire bottle of probiotic supplements. You can learn more about this in the video below:

Here’s a list of some fantastic fermented foods you should be consuming on a regular basis:
Kefir (fermented milk)

If you’re not making these foods yourself, it’s extremely important to buy brands that don’t pasteurize their food which is extremely common. The process of pasteurization kills a large percentage of the bacteria which totally defeats the purpose of consuming fermented food. I highly recommend you make all your own fermented food because it’s fun and extremely easy.

In addition to fermented food you’ll also need specific nutrients, foods and spices to boost your immune system and support a healthy microflora such as:
Vitamin C
Vitamin D
Coconut Oil
Apple Cider Vinegar

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